Background and Objective: Identification of potential risks in laboratories and trying to create safe conditions for the staff is very important from different aspects. The main objective of this study was to evaluate the potential risks in the laboratories of three research centers affiliated to Iranian Fisheries Science Research Institute.

Materials and Methods: In order to assess and classify risks associated with working in the laboratories (11 laboratories of the Persian Gulf and Oman Sea Ecological Research Center, 9 laboratories of National Shrimp Research Center and 2 laboratories of National Aquatic Organisms Processing Center), the method of "Failure Mode Effects Analysis" (FMEA) as well as statistical methods (concerning compare means) were used.

Results: The risk levels in all the laboratories of the Persian Gulf and Oman Sea Ecological Research Center, except for benthos laboratory, could be evaluated as moderate or high. Only in the case of the sample preparation laboratory, significant differences between the values ​​of RPN before and after corrective action was observed. However, in this case the corrective actions have not been effective in decreasing the risk level. In most laboratories of National Shrimp Research Center, the corrective actions were effective in reducing the risk levels (with the exception of three laboratories). In both laboratories of National Aquatic Organisms Processing Center, after the corrective actions, the risk levels were sharply reduced.

Conclusion: Considering the high level of risk in many evaluated laboratories, appropriate corrective actions were proposed. But after the second-stage evaluation, it was realized that the proposed corrective measures in some laboratories (especially in the Persian Gulf and Oman Sea Ecological Research Center) were notperformed sufficiently and hence the risk still was remained at critical or semi-critical level